Twin Pregnancies and Fetal Brain Injury
- Twin pregnancies are associated with increased risk of mortality and neurological morbidity, especially in monochorionic twins who share a single placenta.
- Potential mechanisms of fetal brain injury in monochorionic twins include:
- Hypoxemia
- Ischaemia
- Cardiac failure
- Anemia-polycythemia
- Embolic complications (in survivors of co-twin demise)
- Vaso-occlusive injury
- Inflammatory injury
Complications in Monochorionic Twins
- Common fetal complications include:
- Selective fetal growth restriction (sFGR)
- Twin-twin transfusion syndrome (TTTS)
- Twin anemia polycythemia sequence (TAPS)
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