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Last updated: 05 June 2024 Print

Fenfluramine

Information
Fenfluramine

Overview

  • Generic Name: Fenfluramine
  • Brand Names: Fintepla (current), Pondimin (previously)
  • Drug Class: Serotonergic agent, anorectic (appetite suppressant)

Chemical Information

  • Chemical Formula: C12H16F3N
  • Molecular Weight: 231.26 g/mol

Indications

  • Dravet Syndrome: Used as an adjunctive treatment for seizures in patients with Dravet syndrome.
  • Appetite Suppressant: Previously used for weight loss (withdrawn due to adverse effects).

Mechanism of Action

  • Serotonin Release: Promotes the release of serotonin and inhibits its reuptake, leading to increased serotonin levels in the brain.
  • Interaction with Receptors: Modulates various serotonin receptors, contributing to its therapeutic and adverse effects.

Pharmacokinetics

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