Overview
- Generic Name: Fenfluramine
- Brand Names: Fintepla (current), Pondimin (previously)
- Drug Class: Serotonergic agent, anorectic (appetite suppressant)
Chemical Information
- Chemical Formula: C12H16F3N
- Molecular Weight: 231.26 g/mol
Indications
- Dravet Syndrome: Used as an adjunctive treatment for seizures in patients with Dravet syndrome.
- Appetite Suppressant: Previously used for weight loss (withdrawn due to adverse effects).
Mechanism of Action
- Serotonin Release: Promotes the release of serotonin and inhibits its reuptake, leading to increased serotonin levels in the brain.
- Interaction with Receptors: Modulates various serotonin receptors, contributing to its therapeutic and adverse effects.
Pharmacokinetics
