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Last updated: 04 June 2024 Print

Benign Familial Infantile Seizures

Information
Benign Familial Infantile SeizuresBenign familial neonatal-infantile seizures

Epidemiology

  • Global Reports: BFIE cases have been reported worldwide.
  • Prevalence and Incidence: Remain unknown.

Clinical Description

  • Age of Onset: Seizures usually occur between 3 to 8 months of life.
  • Seizure Characteristics:
    • Clusters of 8-10 episodes a day.
    • Each episode lasts 2-5 minutes over a few days.
    • Typically focal but can become generalized.

    Etiology

    • Motor arrest, unresponsiveness, head and/or eye deviation to one side.
    • Staring, fluttering of eyelids, grunting, cyanosis.
    • Diffuse hypertonia and unilateral or bilateral clonic jerks of the limbs.

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