Definition and Overview

  • Posterior Fossa Syndrome (PFS): A constellation of neurological and behavioral symptoms occurring in children following posterior fossa tumor resection.
  • Incidence: Occurs in approximately 8% of children undergoing posterior fossa tumor surgery.
  • Etiology:
    • Damage to the cerebellum and cerebello-thalamo-cortical pathways.
    • Post-surgical edema, ischemia, or disruption of white matter tracts.
    • Affects structures like the dentate nuclei, superior cerebellar peduncles, and their projections.
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