| Choice Antiepileptic Drug (AED)medication in children |
| Seizure type/syndrome |
First Line |
Second Line |
Drugs to avoid |
| Focal seizures |
CBZ,LTG,OXC,TPM,VPA |
CLB,GBP,LEV,PHT,TGB,ZON,PGN |
|
| Generalised Seizures |
|
|
|
| Absence |
ESM,LTG,VPA |
CLB,CLM,TPM |
CBZ,GBP,OXC,TGB,VGB |
| GTC |
CBZ,LTG,VPA,TPM |
CLB,LEV,OXC,ZON |
TGB,VGB |
| Myoclonic |
VPA,TPM |
LTG,CLB,CLM,LEV,Piracetam |
CBZ,GBP,OXC,TGB,VGB |
| Tonic |
LTG,VPA |
CLB,CLM,LEV,TPM |
CBZ,OXC |
| Atonic |
LTG,VPA |
LEV,TPM,CLB,CLM |
CBZ,OXC,PHT |
| Childhood absence epilepsy |
ESM,LTG,VPA |
LEV,TOP |
CBZ,OXC,PHT,TGB,VGB |
| Juvenile absence epilepsy |
LTG,VPA |
LEV,TPM |
CBZ,OXC,PHT,TGB,VGB |
| Juvenile myoclonic epilepsy |
LTG,VPA |
CLB,CLM,TPM,LEV |
CBZ,OXC,PHT,TGB,VGB |
| BECTS |
CBZ,LTG,OXC,VPA |
LEV,TPM |
|
| BCOS |
CBZ,LTG,OXC,VPA |
LEV,TPM |
|
| Infantile spasms |
VGB,Steroids |
CLB,CLM,VPA,TPM |
CBZ,OXC |
| Dravets |
VPA,TPM,CLB,CLM |
LEV,Stiripentol |
CBZ,LTG,OXC,VGB |
| Lennox-Gastuat Syndrome |
VPA,LTG,TPM |
CLB,CLM,ESM,LEV,RUF |
CBZ,OXC |
| Landau-Kleffner syndrome |
Steroids,LTG,VPA |
LEV,TPM |
CBZ,OXC |
| CSWS |
Steroids,CLB,CLM,VPA,LTG,ESM |
LEV,TPM |
CBZ,OXC,VGB |
| Myoclonic astatic epilepsy |
CLB,CLM,VPA,TPM |
LEV,LTG |
CBZ,OXC |
