Disruption at any of the stages in metabolism could contribute to primary and/or secondary contributions to ASD
Possible Role for Metabolism in the Pathogenesis of ASD
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Overview of Metabolism:
- Metabolism encompasses biochemical processes for:
- Converting food into energy to power cells
- Synthesizing cellular components
- Eliminating waste (López-Otín et al., 2016)
Role of Metabolism in Altered Cognition in ASD
- Disruption at any stage could contribute to ASD through primary and/or secondary pathways (Cheng et al., 2017; Frye, 2015; Schiff et al., 2011).
- Metabolic disturbances at the cellular level, particularly in neuronal pathways, may cause synaptic dysfunction underlying altered cognitive development in ASD.
Secondary Contributions of Metabolism to ASD
- Metabolism encompasses biochemical processes for:
