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Saturday, 04 January 2025

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Assuming effects is required, the following 60 results were found.

  1. Lennox-Gastaut Syndrome (LGS)https://cnke.org/articles/247

    problems may arise from a combination of factors, including the epilepsy itself, abnormal network characteristics, and the effects of medications. Seizure Types Tonic Seizures: The most characteristic type of seizure in LGS. Considered a prerequisite...

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  2. Infantile Spasms Syndromehttps://cnke.org/articles/269

    New treatments with mTOR inhibitors proposed for drug-resistant epilepsy, including ISs, but faced criticism due to side effects and poor efficacy over time (Ji S et al., 2017; Franz DN et al., 2018; Curatolo P et al., 2018) Neurofibromatosis Type 1...

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  3. Migraine in childhoodhttps://cnke.org/articles/358

    headache features, associated symptoms, and overall disability Goal: Quick-acting, effective therapy with minimal side effects Medication and Treatment Options Triptans: Most effective for pain relief Less effect on associated nausea and vomiting...

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  4. Metabolic derangements and Autismhttps://cnke.org/articles/126

    affecting downstream cellular processes in the body and brain Decreased synthesis of essential vitamins by the microbiome Effects on the immune system (Buie, 2015; Heintz-Buschart and Wilmes, 2018; Mulle et al., 2013) Improving Behavioral Outcomes:...

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  5. Transcranial Magnetic Stimulation (TMS) in Autism Spectrum Disordershttps://cnke.org/articles/182

    TMS Repetitive TMS (rTMS) Low-frequency (≤1 Hz): Generally inhibitory High-frequency (≥5 Hz): Generally excitatory Observed Effects of TMS in ASD A. Behavioral Changes Reduction in repetitive and stereotypic behaviors Improved social responsiveness...

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  6. Chronic Daily Headache Disorderhttps://cnke.org/articles/236

    Definition and Prevalence Chronic daily headache is diagnosed based on the presence of headaches occurring for 15 or more days per month, over a period of three consecutive months, without any underlying organic pathology. These headaches last for more...

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  7. Valproatehttps://cnke.org/articles/287

    of women on valproate. Polycystic ovary syndrome and other endocrine issues in women. Central Nervous System (CNS) Effects: Generally does not cause drowsiness or significant cognitive effects. Valproate encephalopathy is rare. Tremor: Can be mild to...

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  8. Lisdexamfetamine Dimesylatehttps://cnke.org/articles/148

    medications. Long-term trials show sustained symptom control and functional improvement. Onset of Action: Clinical effects seen within 1-2 hours after administration. Full effects maintained throughout the day. Safety and Side Effects Common Adverse...

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  9. Circadian Rhythm Sleep-Wake Disorders (CRSWD)https://cnke.org/articles/164

    Medications: Off-label use requires careful consideration of pediatric-specific factors such as metabolism and polytherapy effects. Regular monitoring minimizes adverse effects and optimizes efficacy. Genetics of Circadian Disorders Molecular Basis:...

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  10. Cenobamatehttps://cnke.org/articles/308

    were in line with data published for adults No serious adverse events occurred in their cohort. Most frequent adverse effects in their cohort were somnolence/fatigue which occurred during up-titration, in line with other reports[4]. Less frequently...

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  11. Gilles De La Tourette Syndromehttps://cnke.org/articles/260

    Dopamine receptor antagonists are indicated. Pimozide is often used at low doses (1–4 mg/day) due to relatively few side effects (Comings, 1990). Haloperidol should only be used if risperidone fails. Risperidone and pimozide are more effective than...

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  12. Migrainehttps://cnke.org/articles/234

    Overview Migraines are severe, often bilateral, throbbing headaches commonly located in the temples or frontal regions of the head. They affect different age groups with varying prevalence rates: 2-5% in preschool children, 10% in school-aged children,...

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  13. Self Injurious Behaviour (SIB) https://cnke.org/articles/229

    sensory stimulus that replicates the sensory experience of SIB. For example, a hand massager can be used to mimic the effects of hand mouthing or biting.By offering uninterrupted access to these stimuli, it may reduce the desire to seek reinforcement...

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  14. Opsoclonus Myoclonus Ataxia Syndromehttps://cnke.org/articles/330

    may be performed over 12 mo, which may be more rapid with steroid-sparing agent. Longer treatment may be needed. Adverse effects Potential side effects include irritability, hypertension, hyperglycemia, weight gain infections, and osteopenia, which may...

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  15. Fenfluraminehttps://cnke.org/articles/280

    seizures in patients with Dravet syndrome. Appetite Suppressant: Previously used for weight loss (withdrawn due to adverse effects). Mechanism of Action Serotonin Release: Promotes the release of serotonin and inhibits its reuptake, leading to increased...

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  16. Helmet therapy for cranial deformitieshttps://cnke.org/articles/helmet-therapy-for-cranial-deformities

    benefit of helmets over repositioning techniques and physiotherapy. Helmets can be costly and resource-intensive. Adverse Effects Skin irritation or pressure sores. Discomfort or poor tolerance by the infant. Parental stress related to maintenance and...

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  17. Levetiracetamhttps://cnke.org/articles/278

    varies based on age and weight. Typically starts at 10 mg/kg twice daily, with adjustments based on clinical response. Side Effects Common: Drowsiness, dizziness, fatigue, headache, irritability. Serious: Behavioral changes (aggression, agitation),...

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  18. NGN-401https://cnke.org/articles/160

    dendritic spine morphology and synaptic density. Safety Profile: Dose-escalation studies confirmed minimal off-target effects and no evidence of systemic toxicity. Clinical Trials Initial Phase I/II clinical trials have focused on safety, tolerability,...

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  19. Idiopathic Intracranial Hypertensionhttps://cnke.org/articles/178

    function (per IIHTT study). Topiramate: Dual role: Anti-migraine and appetite suppression. Caution for cognitive side effects and depression. Headache Management: Migrainous phenotype: Use migraine preventives that do not promote weight gain. Address...

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  20. Pyridoxal 5 Phosphate Dependent Epilepsyhttps://cnke.org/articles/228

    PNPO deficiency (OMIM 6032870) is an autosomal recessive inborn error of metabolism that leads to a seizure disorder, presenting in the newborn period (neonatal epileptic encephalopathy) or early infancy, that can be treated with pyridoxal 5’-phosphate...

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Results 1 - 20 of 60