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Friday, 04 April 2025

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Assuming effects is required, the following 72 results were found.

  1. Lennox-Gastaut Syndrome (LGS)https://cnke.org/articles/50

    problems may arise from a combination of factors, including the epilepsy itself, abnormal network characteristics, and the effects of medications. Seizure Types Tonic Seizures: The most characteristic type of seizure in LGS. Considered a prerequisite...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  2. Infantile Spasms Syndromehttps://cnke.org/articles/269

    New treatments with mTOR inhibitors proposed for drug-resistant epilepsy, including ISs, but faced criticism due to side effects and poor efficacy over time (Ji S et al., 2017; Franz DN et al., 2018; Curatolo P et al., 2018) Neurofibromatosis Type 1...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  3. Migraine in childhoodhttps://cnke.org/articles/358

    headache features, associated symptoms, and overall disability Goal: Quick-acting, effective therapy with minimal side effects Medication and Treatment Options Triptans: Most effective for pain relief Less effect on associated nausea and vomiting...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  4. Metabolic derangements and Autismhttps://cnke.org/articles/126

    affecting downstream cellular processes in the body and brain Decreased synthesis of essential vitamins by the microbiome Effects on the immune system (Buie, 2015; Heintz-Buschart and Wilmes, 2018; Mulle et al., 2013) Improving Behavioral Outcomes:...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  5. Transcranial Magnetic Stimulation (TMS) in Autism Spectrum Disordershttps://cnke.org/articles/182

    TMS Repetitive TMS (rTMS) Low-frequency (≤1 Hz): Generally inhibitory High-frequency (≥5 Hz): Generally excitatory Observed Effects of TMS in ASD A. Behavioral Changes Reduction in repetitive and stereotypic behaviors Improved social responsiveness...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  6. Vigabatrin for Infantile Spasmshttps://cnke.org/articles/255

    and normalizing EEG in many cases. Particularly beneficial in symptomatic IS with tuberous sclerosis. Safety and Side Effects: Risk of visual field defects with long-term use. Requires regular ophthalmologic monitoring. Clinical Considerations: Should...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  7. Chronic Daily Headache Disorderhttps://cnke.org/articles/39

    Definition and Prevalence Chronic daily headache is diagnosed based on the presence of headaches occurring for 15 or more days per month, over a period of three consecutive months, without any underlying organic pathology. These headaches last for more...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  8. Valproatehttps://cnke.org/articles/287

    of women on valproate. Polycystic ovary syndrome and other endocrine issues in women. Central Nervous System (CNS) Effects: Generally does not cause drowsiness or significant cognitive effects. Valproate encephalopathy is rare. Tremor: Can be mild to...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  9. Duchenne Muscular Dystrophyhttps://cnke.org/articles/225

    Clinical Management Multidisciplinary Approach: Focuses on respiratory, cardiac, orthopedic, and nutritional issues, and effects of corticosteroid therapy. Genetic counseling is critical. Physiotherapy and Orthotics: Regular therapy helps maintain...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  10. Lisdexamfetamine Dimesylatehttps://cnke.org/articles/148

    medications. Long-term trials show sustained symptom control and functional improvement. Onset of Action: Clinical effects seen within 1-2 hours after administration. Full effects maintained throughout the day. Safety and Side Effects Common Adverse...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  11. Infantile Spasms: Treatmenthttps://cnke.org/articles/256

    First-Line Therapies: ACTH or Corticosteroids: High efficacy in stopping spasms and resolving hypsarrhythmia. Consider side effects (e.g., hypertension, infection risk). Vigabatrin: Particularly effective in Tuberous Sclerosis Complex (TSC). Risk of...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  12. Circadian Rhythm Sleep-Wake Disorders (CRSWD)https://cnke.org/articles/164

    Medications: Off-label use requires careful consideration of pediatric-specific factors such as metabolism and polytherapy effects. Regular monitoring minimizes adverse effects and optimizes efficacy. Genetics of Circadian Disorders Molecular Basis:...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  13. Cenobamatehttps://cnke.org/articles/308

    were in line with data published for adults No serious adverse events occurred in their cohort. Most frequent adverse effects in their cohort were somnolence/fatigue which occurred during up-titration, in line with other reports[4]. Less frequently...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  14. Gilles De La Tourette Syndromehttps://cnke.org/articles/260

    Dopamine receptor antagonists are indicated. Pimozide is often used at low doses (1–4 mg/day) due to relatively few side effects (Comings, 1990). Haloperidol should only be used if risperidone fails. Risperidone and pimozide are more effective than...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  15. Bromideshttps://cnke.org/articles/bromides

    the half-life. Steady-State Concentration: Takes ~7–8 weeks to achieve. Drug Interactions: CNS depressant; potentiates effects of other CNS-active drugs. Does not induce/inhibit liver enzymes or affect protein binding. Therapeutic Drug Monitoring: Serum...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  16. Migrainehttps://cnke.org/articles/37

    Overview Migraines are severe, often bilateral, throbbing headaches commonly located in the temples or frontal regions of the head. They affect different age groups with varying prevalence rates: 2-5% in preschool children, 10% in school-aged children,...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  17. Self Injurious Behaviour (SIB) https://cnke.org/articles/32

    sensory stimulus that replicates the sensory experience of SIB. For example, a hand massager can be used to mimic the effects of hand mouthing or biting.By offering uninterrupted access to these stimuli, it may reduce the desire to seek reinforcement...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  18. Augmentative and Alternative Communication (AAC)https://cnke.org/articles/250

    Definition and Purpose AAC provides alternative methods of communication for individuals with severe speech impairments or lack of speech. Aims to enable independent communication and improve quality of life, regardless of temporary or long-term speech...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  19. Opsoclonus Myoclonus Ataxia Syndromehttps://cnke.org/articles/330

    may be performed over 12 mo, which may be more rapid with steroid-sparing agent. Longer treatment may be needed. Adverse effects Potential side effects include irritability, hypertension, hyperglycemia, weight gain infections, and osteopenia, which may...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles

  20. Fenfluraminehttps://cnke.org/articles/280

    seizures in patients with Dravet syndrome. Appetite Suppressant: Previously used for weight loss (withdrawn due to adverse effects). Mechanism of Action Serotonin Release: Promotes the release of serotonin and inhibits its reuptake, leading to increased...

    • Type: Article
    • Author: Editor CNKE
    • Category: Articles
Results 1 - 20 of 72