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Alexander Disease

Type: Article Author: Editor CNKE Category: Articles Language: * Editor:
Editor(s)
Alexander disease is a rare neurodegenerative disorder caused by mutations in the glial fibrillary acidic protein, a type III intermediate filament protein expressed in astrocytes. Introduction Definition: Alexander disease is a progressive disorder of...
07 January 2025
https://cnke.org/articles/253

Wilson Disease: Copper, Neurology, and the Legacy of a Medical Pioneer

Type: Article Author: Biju Hameed Category: Historical Vignettes Language: *
In the rich tapestry of medical history some threads stand out not only for their scientific significance but also for their human drama. The story of Wilson disease (WD), or Wilson's disease as it was originally known, is one of such fascinating...
04 May 2025
https://cnke.org/historical-vignettes/wilson-disease-copper-neurology-and-the-legacy-of-a-medical-pioneer

Alexander Disease

Type: Tag Author: Editor CNKE Language: *
https://cnke.org/topics/alexander-disease

CNS Degenerative Disorders of Childhood

Type: Article Author: Editor CNKE Category: Articles Language: * Editor:
Editor(s)
matter. Infantile: fatal Variants are slowly progressive Adult variant (autosomal dominant) with ovarian dysgenesis Alexander disease AD GFAP gene Infancy Macrocephaly Ataxia Spasticity Demyelination; rosenthal fibers characteristic of biopsy. Fatal...
08 June 2024
https://cnke.org/articles/315

Significant historical advances, theories, and practices surrounding cerebral palsy from ancient times through the mid-20th century

Type: Article Author: Editor CNKE Category: Historical Vignettes Language: *
Significant historical advances, theories, and practices surrounding cerebral palsy from ancient times through the mid-20th century. Historical Timeline 1196–1190 BCE: Pharaoh Siptah exhibits earliest recorded CP-like symptoms. 1580–1350 BCE: Stele of...
29 April 2025
https://cnke.org/historical-vignettes/significant-historical-advances-theories-and-practices-surrounding-cerebral-palsy-from-ancient-times-through-the-mid-20th-century

Hydrocephalus: Echoes from Antiquity to Modern Neuroscience

Type: Article Author: Editor CNKE Category: Historical Vignettes Language: *
Hydrocephalus, derived from the Greek words hydro (water) and kephalē (head), meaning "water in the brain," has intrigued, baffled, and challenged humanity from ancient civilizations to today's advanced neurosurgical era. THE PRE-CHRISTIAN ERA THE...
06 May 2025
https://cnke.org/historical-vignettes/hydrocephalus-echoes-from-antiquity-to-modern-neuroscience

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