Short Sharp Spikes (Pathological)

  • Definition: Brief epileptiform discharges indicative of underlying cortical irritability or epilepsy.
  • Characteristics:
    • Typically higher amplitude (>50 µV)
    • Slightly longer duration, clearer epileptiform morphology
    • Often focal, associated with cortical abnormalities or epilepsy syndromes
    • Commonly accompanied by aftergoing slow-wave components
    • Can occur at any sleep stage or awake state
  • Clinical Significance: Often associated with epilepsy or underlying neurological disorders

cf Small Sharp Spikes (BETS)


FeatureSmall Sharp Spikes (BETS)Short Sharp Spikes (Pathologic)
Amplitude <50 µV Usually >50 µV
Duration <50 ms Typically slightly longer, clearer epileptiform morphology
Localization Bilateral temporal, independent Usually focal, cortical irritability
Sleep Stage Drowsiness/N1-N2 sleep stages Any sleep stage or awake
Aftergoing Slow Wave Typically absent Frequently present
Clinical Relevance Benign EEG variant Often pathologic, associated with epilepsy