Microcephaly

Definition and Diagnostic Criteria

  • Fetal microcephaly is defined as:
    • Head circumference >2SD below mean or
    • Below the 3rd centile for gestational age

    Inheritance and Familial Factors

    • Controversies about optimal reference charts and ethnic adaptations
    • Fetal charts differ from gestational-age adjusted postnatal charts
    • Fetal head circumference charts are not sex-specific

    Outcome Based on Severity

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