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Last updated: 04 January 2025 Print

Self-Limited Epilepsy with Centrotemporal Spikes (SeLECTS)

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Benign Epilepsy of Childhood with Centrotemporal SpikesBenign Rolandic Epilepsychildhood epilepsy with centrotemporal spikes

(formerly called childhood epilepsy with centrotemporal spikes, benign epilepsy of childhood with centrotemporal spikes or Benign Rolandic Epilepsy)

  • Self-Limited Epilepsy with Centrotemporal Spikes (SeLECTS), is the most common focal epilepsy syndrome of childhood, accounting for 15–20% of all childhood epilepsies.
  • age-dependent epilepsy, with a typical onset at 5–8 years
  • incidence is approximately 6.1 per 100,000 children aged <16 years per year (Specchio N et al., 2022)
  • Both sexes are affected, with a slight male predominance (60%)
  • Most of the time it is a self-limiting epileptic syndrome, with seizure remission within adolescence
  • Seizures are overall relatively infrequent, with 60–70% of patients experiencing two to ten seizures lifetime and 10–20% only one
  • Rarely Children with SeLECTS evolve to Developmental and/or Epileptic Encephalopathy with spike-wave activation in sleep (D/EE-SWAS)which is distinguished by cognitive and language regression
  • D/EE-SWAS incorporates the several syndromes previously named Landau-Kleffner syndrome, Epileptic encephalopathy with continuous spike-waves during sleep and Atypical benign partial epilepsy (pseudo-Lennox syndrome). All these conditions share some EEG features.

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