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Last updated: 29 December 2024 Print

Ataxias: Differential Diagnosis

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Cerebellar Ataxias

Acute Ataxias

Vascular Disorders

  • Cerebellar Ischemia: Reduced blood flow to the cerebellum leading to infarction.
  • Cerebellar Hemorrhage: Bleeding within the cerebellum, often associated with hypertension or anticoagulation therapy.

Medications and Toxins

  • Antiepileptic Drugs:

    • Phenytoin
    • Carbamazepine
    • Oxcarbazepine
    • Lacosamide
    • Lamotrigine
    • Zonisamide
    • Rufinamide
      (Particularly in the setting of hyperammonemia, with valproic acid, benzodiazepines, phenobarbital, and felbamate.)

    Infections

    • Cytarabine
    • Fluorouracil
    • Capecitabine
    • Hexamethylmelamine
    • Procarbazine
    • Vincristine
    • Cisplatin
    • Oxaliplatin

    Subacute Ataxias

    Chemotherapy Agents:

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