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Last updated: 29 December 2024 Print

Lisdexamfetamine Dimesylate

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Attention Deficit Hyperactivity DisorderLisdexamfetamine Dimesylate

Lisdexamfetamine Dimesylate

  • Brand Names: Vyvanse, Elvanse.lisdexamphetamine
  • Drug Class: Prodrug stimulant.
  • Mechanism of Action:
    • Lisdexamfetamine is a prodrug of d-amphetamine.
    • Activated enzymatically in the bloodstream to d-amphetamine.
    • Increases availability of dopamine and norepinephrine in the synaptic cleft.
    • Improves executive function, attention, and impulse control.

    Indications

    • Requires enzymatic conversion for activation, reducing potential for abuse.
    • Extended-release formulation provides sustained symptom control over 12-14 hours.

    Dosage and Administration

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