Overview
- Generic Name: Levetiracetam
- Brand Names: Keppra, Spritam, Elepsia, Roweepra
- Drug Class: Antiepileptic drug (AED)
Chemical Information
- Chemical Formula: C8H14N2O2
- Molecular Weight: 170.21 g/mol
Indications
- Epilepsy:
- Partial-onset seizures (with or without secondary generalization)
- Myoclonic seizures in patients with juvenile myoclonic epilepsy
- Primary generalized tonic-clonic seizures in patients with idiopathic generalized epilepsy
Mechanism of Action
- Unknown Precise Mechanism: Levetiracetam's exact mechanism is not fully understood.
- Binding to SV2A: It is believed to modulate synaptic vesicle protein 2A (SV2A), which is involved in the release of neurotransmitters.
- Inhibition of N-type calcium channels: May inhibit these channels, reducing neurotransmitter release.
Pharmacokinetics